• Kögel J.F., Timoshkin A.Y., Schröder A., Lork E., Beckmann J., Al(OCArF3)3 - A Thermally Stable Lewis Superacid Chem. Science, 2018, doi 10.1039/c8sc02981d, IF = 9.1

    The adduct free Lewis superacid Al(OCArF3)3 was obtained by the reaction of ArF3COH with AlEt3 and fully characterized (ArF = C6F5). It comprises a high thermal stability up to 180 °C and a distinct reactivity towards Lewis bases, as exemplified by the isolation of the neutral adducts Al(OCArF3)·D (D = MeCN, THF, Et2O, pyridine, OPEt3), the fluoride complexes [Q][FAl(OCArF)3] (Q+ = Cs+, Ag+, Tl+, [S(NMe2)3]+, [Ph3C]+, Li+, [NBu4]+, [FeCp2]+) and the chloride complex [Ph3C][ClAl(OCArF)3].

  • Agafonova A.V., Smetanin I.A., Rostovskii N.V., Khlebnikov A.F., Novikov M.S. Expedient synthesis of 3-hydroxypyrroles via Bu3SnH-triggered ionic 5-exo-trig-cyclization of 5-chloro-3-azamuconoate derivatives Org. Chem. Front. 2018, doi 10.1039/c8qo00982a, IF=5.455

    An unprecedented application of tributyltin hydride (TBTH) as a reagent for the reductive ionic 1,5-cyclization of 3-azamuconoates (3-azahexa-2,4-dienedioates) is described. A novel 1,5-exo-trig-cyclization of 5-chloro-3-azamuconoates was used as a base for the development of an effective two-step method for the preparation of 4-hydroxy-1H-pyrrole-3-carboxylic and 3-hydroxy-1H-pyrrole-2,4-dicarboxylic acids derivatives from readily available diazo esters and 2-chloro-2H-azirines or 4-chloroisoxazoles. The experimental results, as well as the DFT calculations of the pyrroles formation, are in good agreement with the ionic mechanism involving the initial hydride attack at the CN bond of the azamuconoate followed by tin-promoted 1,5-cyclization.

  • Anastasia I. Solomatina, Pavel S. Chelushkin, Tatiana O. Abakumova, Vladimir A. Zhemkov, Mee-Whi Kim, Ilya Bezprozvanny, Vladislav V. Gurzhiy, Alexey S. Melnikov, Yuri A. Anufrikov, Igor O. Koshevoy, Shih-Hao Su, Pi-Tai Chou, Sergey P. Tunik Reactions of Cyclometalated Platinum(II) [Pt(N^C)(PR3)Cl] Complexes with Imidazole and Imidazole-Conjugated Biomolecules: Fine-Tuning Reactivity and Photophysical Properties via Ligand Design, Inorg. Chem., 2018. Article in Press. DOI: 10.1021/acs.inorgchem.8b02204 IF=4.7

    Chemical and structural aspects of the [Pt(NC)PR3Cl] complexes conjugation with ubiquitin and albumin were investigated in detail. Rapid, selective, and quantitative coordination of the platinum complex to imidazole function of the proteins enabled their regioselective labeling and also paves the way to application of the conjugates in quantitative mapping of oxygen concentration in cells using PLIM microscopy.

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